產(chǎn)品編號 | bsm-51333M-BF488 |
英文名稱 | Mouse Anti-RAB18/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的小鼠抗G蛋白家族RAB18蛋白單克隆抗體 |
別 名 | RAB18; RAB18 member RAS oncogene family; RAB18 small GTPase; RAB18_HUMAN; RAB18LI1; Ras-related protein Rab-18. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 G蛋白信號 |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 3A8 |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 23kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | Recombinant human RAB18 protein |
亞 型 | IgG1 |
純化方法 | affinity purified by Protein G |
儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] Function: Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side Tissue Specificity: Ubiquitous. Similarity: Belongs to the small GTPase superfamily. Rab family. Database links: Entrez Gene: 22931 Human Entrez Gene: 19330 Mouse Omim: 602207 Human SwissProt: Q9NP72 Human SwissProt: P35293 Mouse Unigene: 406799 Human Unigene: 132802 Mouse Unigene: 472772 Mouse Unigene: 53248 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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