| 產(chǎn)品編號(hào) | bs-17282R-PE |
| 英文名稱 | Rabbit Anti-SCGB3A2/PE Conjugated antibody |
| 中文名稱 | PE標(biāo)記的子宮珠蛋白相關(guān)蛋白1/肺炎分泌蛋白1抗體 |
| 別 名 | LU103; Pneumo secretory protein 1; PnSP-1; PNSP1; Secretoglobin family 3A member 2; UGRP1; Uteroglobin-related protein 1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Horse, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 8kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SCGB3A2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Uteroglobin-related protein 1 is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis, and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation Function: In addition to regulating thyroid-specific expression of genes, thyroid transcription factor controls the transcription of genes specifically expressed in lung, such as surfactant proteins and uteroglobin. Mice lacking Ttf1 die immediately after birth from respiratory failure caused by profoundly hypoplastic lungs. The UGRP1 gene encodes a uteroglobin-related protein and is a downstream target of TITF1. Subcellular Location: Secreted. Database links: Entrez Gene: 117156 Human Omim: 606531 Human SwissProt: Q96PL1 Human Unigene: 483765 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
