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Rabbit Anti-TRNT1/BF488 Conjugated antibody (bs-17149R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-17149R-BF488
英文名稱 Rabbit Anti-TRNT1/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的TRNT1蛋白抗體
別    名 AA408384; C76540; CCA adding; CCA1; CGI 47; EC 2.7.7.25; Mitochondrial CCA adding tRNA nucleotidyltransferase; Mitochondrial tRNA nucleotidyl transferase, CCA adding; mt CCA adding enzyme; mt Trat; mt tRNA adenylyltransferase; mt tRNA CCA diphosphorylase; mt tRNA CCA pyrophosphorylase; MtCCA; MTO2; TRNT1_HUMAN; TRMU; tRNA nucleotidyl transferase; tRNA nucleotidyl transferase CCA adding 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRNT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 [PubMed 17204286]).[supplied by OMIM, Aug 2009]

Function:
TRNT1 belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. It adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates.

Subunit:
Monomer, and homodimer; disulfide-linked.

Subcellular Location:
Mitochondrial

Similarity:
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

Database links:

Entrez Gene: 51095 Human

Entrez Gene: 70047 Mouse

Entrez Gene: 312616 Rat

Entrez Gene: 415249 Zebrafish

Omim: 612907 Human

SwissProt: Q96Q11 Human

SwissProt: Q8K1J6 Mouse

SwissProt: Q4VBH2 Rat

SwissProt: Q6IQR7 Zebrafish

Unigene: 567495 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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