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Rabbit Anti-ZNF674/Gold Conjugated antibody (bs-16524R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-16524R-Gold
英文名稱 Rabbit Anti-ZNF674/Gold Conjugated antibody
中文名稱 膠體金標記的鋅指蛋白674抗體
別    名 MENTAL RETARDATION, X LINKED 92; MRX92; ZN674_HUMAN; Zinc finger family member 674; Zinc finger protein 674; ZNF673B.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 轉錄調節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, 
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZNF674
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]

Function:
ZNF674 belongs to the krueppel C2H2-type zinc-finger protein family and contains 11 C2H2-type zinc fingers and 1 KRAB domain. ZNF674 may be involved in transcriptional regulation. Defects in ZNF674 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.

Subcellular Location:
Nuclear

Tissue Specificity:
Expressed in testis.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 11 C2H2-type zinc fingers.
Contains 1 KRAB domain.

Database links:

Entrez Gene: 641339 Human

Omim: 300573 Human

SwissProt: Q2M3X9 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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