| 產(chǎn)品編號 | bs-16082R-BF488 |
| 英文名稱 | Rabbit Anti-FGD6/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的FGD6蛋白抗體 |
| 別 名 | FYVE, RhoGEF and PH domain containing protein 6; ZFYVE24; FGD6_HUMAN; Zinc finger FYVE domain containing protein 24. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 161kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FGD6 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: FGD6 is a 1,430 amino acid cytoplasmic protein that belongs to the FGD family and exists as two alternatively spliced isoforms. Thought to activate Cdc42 by exchanging bound GDP for free GTP, FGD6 is also implicated in maintenance of the actin cytoskeleton and regulating cell shape. Encoded by a gene that maps to human chromosome 12q22, FGD6 contains one FYVE-type zinc finger, two PH domains and a single DH (DBL-homology) domain. Function: FGD6 may activate CDC42 by exchanging bound GDP for free GTP. It may also play a role in regulating the actin cytoskeleton and cell shape. There are two isoforms. Subcellular Location: Cytoplasm (Probable). Cytoplasm, cytoskeleton (Probable). Database links: Entrez Gene: 55785 Human SwissProt: Q6ZV73 Human Unigene: 506381 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
