產(chǎn)品編號 | bs-13777R-RBITC |
英文名稱 | Rabbit Anti-Phospho-5-Lipoxygenase(Ser524)/RBITC Conjugated antibody |
中文名稱 | 羅丹明(RBITC)標(biāo)記的磷酸化5-脂氧合酶抗體 |
別 名 | 5 Lipoxygenase (phospho S524)human mouse; p-5 Lipoxygenase (phospho S524)human mouse; 5 Lipoxygenase (phospho S523)rat; p-5 Lipoxygenase (phospho S523)rat; 5-lipoxygenase; 5 LO; 5LPG; ALOX 5; ALOX5; Arachidonate 5 lipoxygenase; Arachidonic acid 5 lipoxygenase; Leukotriene A4 synthase; LOG 5; LOG5; MGC163204; LOX5_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
產(chǎn)品類型 | 磷酸化抗體 |
研究領(lǐng)域 | 腫瘤 細胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 合成與降解 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 78kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human 5-Lipoxygenase around the phosphorylation site of Ser524 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Function: Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. Subunit: Interacts with ALOX5AP and LTC4S. Subcellular Location: Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Post-translational modifications: Serine phosphorylation by MAPKAPK2 is stimulated by arachidonic acid. Phosphorylation on Ser-523 by PKA has an inhibitory effect. Phosphorylation on Ser-272 prevents export from the nucleus. Similarity: Belongs to the lipoxygenase family. Database links: Entrez Gene: 240 Human Omim: 152390 Human SwissProt: P09917 Human Unigene: 89499 Human Unigene: 9662 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 一级毛片黄久久久免费看A片 | 精品久久九影院私人影院 | 免费无码婬片A片AAA毛多多 | 国产精品伦子伦露脸 | 亚洲欧美国产精品专区久久 | 日韩亚洲在线一区 | 免费h视频在线观看 | 海角社区乱子伦视频播放 | 欧美乱大交XXXXX潮喷 | 欧美A级肉欲艳妇mat | 精品人妻一区二区三区阅读全文 | 无码中文字幕视频一区二区三区 | 国产精品丰满人妻G奶 | 91人妻边做边打电话AⅤ | 成人高潮AA 毛片免费 | 成人红桃a视频一区 | 国产性猛交 XX 乱照片 | 一级黄色视频免费在线观看 | 四虎最新成人永久网站 | 99无码熟妇丰满人妻啪啪 | 91视频在线免费观看 | 国产又粗又黄又爽又硬 | 国产suv一区二区 | 国产无人区码熟妇毛片多 | 亚洲AV无码乱码一区二区 | 免费看无码网站成人A片 | 四川少妇搡BBB搡BBB搡多人伦 | 97人妻人人揉人人澡人人爽国产 | 色大师一区二区三区 | 免费A级毛片无码无遮挡 | 久久久久亚洲AV成人人电影绿帽人妻 | 2019中文在线高清观看电视剧 | 中文字幕免费在线 | 久久亚洲精品国产 | 人超人碰人摸免费视频 | 亚洲无码在线免费观看 | www.高清无码在线观看 | 少妇精品一品二品三品在线观看 | 日本无码人妻波多野结衣杨思敏 | 欧美成人片在线免费观看 |