產(chǎn)品編號 | bs-13760R-Gold |
英文名稱 | Rabbit Anti-DCL-1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的C型凝集素受體CLEC13A抗體 |
別 名 | CD302; CLEC13A; DCL1; C-type lectin domain family 13 member A; C-type lectin BIMLEC; CD302_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 細(xì)胞粘附分子 細(xì)胞表面分子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DCL-1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: DCL-1 is a 232 amino acid single-pass type I membrane protein involved in endocytosis, phagocytosis and cell adhesion and migration. A C-type lectin receptor, DCL-1 is widely expressed with highest levels found in peripheral blood, myeloid and B lymphoid cell lines, liver, ovary and lung. DCL-1 undergoes alternative splicing to produce three isoforms designated DCL-1 isoform 1, isoform 2 (also known as fusion protein variant V34-2) and isoform 3 (also designated fusion protein variant V33-2). DCL-1 isoforms 2 and 3 are produced in malignant lympoma cells, known as Hodgkin and Reed-Sternberg (HRS) cells. DCL-1 contains one C-type lectin domain and is encoded by a gene that maps to human chromosome 2q24.2. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Function: Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. Subcellular Location: Membrane. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 9936 Human Entrez Gene: 66205 Mouse Omim: 612246 Human SwissProt: Q8IX05 Human SwissProt: Q9DCG2 Mouse Unigene: 130014 Human Unigene: 674903 Human Unigene: 227281 Mouse Unigene: 98436 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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