| 產(chǎn)品編號 | bs-15540R-BF488 |
| 英文名稱 | Rabbit Anti-IDI2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的異戊烯基焦磷酸異構(gòu)酶2抗體 |
| 別 名 | IDI2_HUMAN; Isopentenyl-diphosphate Delta-isomerase 2; Isopentenyl pyrophosphate isomerase 2; IPP isomerase 2; IPPI2. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Chicken, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 27kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IDI2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: IDI2 is a 227 amino acid protein that belongs to the IPP isomerase type 1 family. Localizing to the peroxisome, IDI2 is expressed in skeletal muscle and contains one nudix hydrolase domain. IDI2 utilizes magnesium as a cofactor and participates in isoprenoid biosythesis. IDI2 catalytically converts isopentenyl diphosphate (IPP) to its electrophilic isomer, dimethylallyl diphosphate (DMAPP), a substrate for subsequent reactions that synthesize farnesyl diphosphate and, ultimately, cholesterol. The gene encoding IDI2 maps to human chromosome 10p15.3. Segmental copy-number gains to the IDI2 gene may contribute to the pathogenesis of sporadic amyotrophic lateral sclerosis (SALS). SALS, also known as Lou Gehrig's disease, is a motor neuron disease characterized by neuron degeneration Function: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). Subcellular Location: Peroxisome. Tissue Specificity: Detected in skeletal muscle. Similarity: Belongs to the IPP isomerase type 1 family. Contains 1 nudix hydrolase domain. Database links: Entrez Gene: 91734 Human Entrez Gene: 320581 Mouse SwissProt: Q9BXS1 Human SwissProt: Q4FZF0 Mouse Unigene: 591325 Human Unigene: 9270 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
