| 產(chǎn)品編號(hào) | bs-15376R-BF488 |
| 英文名稱(chēng) | Rabbit Anti-GPR114/BF488 Conjugated antibody |
| 中文名稱(chēng) | BF488標(biāo)記的G蛋白偶聯(lián)受體GPR114蛋白抗體 |
| 別 名 | G protein coupled receptor 114; G-protein coupled receptor PGR27; GP114; GP114_HUMAN; GPR114; PGR27; Probable G-protein coupled receptor 114; UNQ2524/PRO6017. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) G蛋白偶聯(lián)受體 G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 57kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPR114 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR114 (G protein-coupled receptor 114), also known as G-protein coupled receptor PGR27, is a 528 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Containing one GPS domain and mapping to human chromosome 16, GPR114 functions as an orphan receptor. Chromosome 16 encodes over 900 genes, comprises nearly 3% of the human genome and is associated with both Rubinstein-Taybi syndrome and Crohn's disease. Function: Orphan receptor. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 1 GPS domain. Database links: Entrez Gene: 221188 Human SwissProt: Q8IZF4 Human Unigene: 187884 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
