91精品少妇一区二区三区蜜桃臀,少妇搡BBBB搡BBB搡失恋,BBB片一毛片A片AA少妇,国产成人无码久久久久毛片朴信惠
掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产黄A片免费观看嫩草影院,強姦婬片A片AAA毛片Mⅴ,成人福利午夜A片公司
Rabbit Anti-ETV6 / Tel/RBITC Conjugated antibody (bs-13115R-RBITC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13115R-RBITC
英文名稱 Rabbit Anti-ETV6 / Tel/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的轉(zhuǎn)錄因子ETV6抗體
別    名 ETS related protein Tel 1; ETS related protein Tel1; ETS translocation variant 6; Ets variant 6; Ets variant gene 6 (TEL oncogene); Ets variant gene 6; ETS-related protein Tel1; ETV 6; ETV6; ETV6_HUMAN; TEL 1; TEL 1 oncogene; TEL; TEL oncogene; TEL/ABL; TEL1; TEL1 oncogene; Transcription factor ETV 6; Transcription factor ETV6.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Chicken, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ETV6/Tel
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
ETV6 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family exhibit varied patterns of tissue expression and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5’-GGAA-3’ element. TEL (for translocation, Ets, leukemia), also designated ETV6, is a member of the Ets family that is involved in specific chromosomal translocations in human leukemia and sarcoma.

Function:
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'.

Subunit:
Can form homodimers or heterodimers with TEL2 or FLI1. Interacts with L3MBTL1 and HDAC9.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression.

DISEASE:
Note=A chromosomal aberration involving ETV6 is found in a form of chronic myelomonocytic leukemia (CMML). Translocation t(5;12)(q33;p13) with PDGFRB. It is characterized by abnormal clonal myeloid proliferation and by progression to acute myelogenous leukemia (AML).
Note=Chromosomal aberrations involving ETV6 are found in a form of acute myeloid leukemia (AML). Translocation t(12;22)(p13;q11) with MN1; translocation t(4;12)(q12;p13) with CHIC2.
Note=Chromosomal aberrations involving ETV6 are found in childhood acute lymphoblastic leukemia (ALL). Translocations t(12;21)(p12;q22) and t(12;21)(p13;q22) with RUNX1/AML1.
Note=A chromosomal aberration involving ETV6 is found in a form of pre-B acute myeloid leukemia. Translocation t(9;12)(p24;p13) with JAK2.
Note=A chromosomal aberration involving ETV6 is found in myelodysplastic syndrome (MDS) with basophilia. Translocation t(5;12)(q31;p13) with ACSL6.
Note=A chromosomal aberration involving ETV6 is found in acute eosinophilic leukemia (AEL). Translocation t(5;12)(q31;p13) with ACSL6.
Note=A chromosomal aberration involving ETV6 is found in myelodysplastic syndrome (MDS). Translocation t(1;12)(p36.1;p13) with MDS2.
Defects in ETV6 are a cause of myeloproliferative disorder chronic with eosinophilia (MPE) [MIM:131440]. A hematologic disorder characterized by malignant eosinophils proliferation. Note=A chromosomal aberration involving ETV6 is found in many instances of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;12) with PDGFRB on chromosome 5 creating an ETV6-PDGFRB fusion protein.
Defects in ETV6 are a cause of acute myelogenous leukemia (AML) [MIM:601626]. AML is a malignant disease in which hematopoietic precursors are arrested in an early stage of development.
Note=A chromosomal aberration involving ETV6 is found in acute lymphoblastic leukemia. Translocation t(9;12)(p13;p13) with PAX5.

Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain.

Database links:

Entrez Gene: 2120 Human

Omim: 600618 Human

SwissProt: P41212 Human

Unigene: 504765 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 rvdoil.com 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
性欧美性受xxxx黑人xyx性爽 | 无套内谢少妇毛片A片软件美国 | 黄色高清无码在线观看 | EEUSS鲁丝片一区二区三区电影 | 日韩在线视频网站 | 亚洲秘 无码一区二区三区蜜桃 | 日韩精品视频一区二区 | 日韩护士一级A片无码 | 成人做爰黄A片免费看直播室 | 中文字幕熟女人妻偷伦 | 婷婷欧美一区二区久久 | 欧美成人精品欧美一级私黄 | 日本三级片在线观看 | 国产无遮挡无黄又爽农村妇女 | 又黑又粗又长黄色视频 | 强伦人妻一区二区三区视频18 | 免费网站在线观看禁18进入 | 少萝裸体 网站春水 | 91人妻人人爽人人精彩 | 国产精品成人无码a 无码 | 3D动漫精品啪啪一区二区免费 | 性一交—乱一性一A片在线播放 | 欧美黄网站在线免费播放 | 国产婬乱片A片AAA毛片下载 | 91人妻一区二区三区蜜臀 | 在线区啪国自产中文字幕 | 亂倫國產一級生活片免費 | 一区二区无码在线 | 国产精品久久久久久久久久不10 | 亚洲精品毛A久久久天爽 | 欧美精品一区在线发布 | 免费黄网站久久久 | 国产精品久久久久高潮色老头 | 少妇内射精品888视频 | 日本黑人乱偷人妻中文 | 色老女人免费视频在线观看 | 99国产精品久久久久久久成人 | 国内成人漫画一二三区 | 日本高清视频啊太大了 | 丰满的少妇乱码一级A片 | 高清无码波多野结衣 |