產(chǎn)品編號 | bs-13279R-BF488 |
英文名稱 | Rabbit Anti-GANC/BF488 Conjugated antibody |
中文名稱 | BF488標(biāo)記的α-葡萄糖苷酶C抗體 |
別 名 | Neutral alphaglucosidase C; Ganc; GANC_HUMAN; Glucosidase alpha neutral C; MGC138256; Neutral alpha glucosidase C; Neutral alpha-glucosidase C; Neutral alphaglucosidase C. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 糖尿病 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 104kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GANC/Neutral alphaglucosidase C |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: A key enzyme in glycogen degradation and metabolism, GANC (glucosidase, α neutral C) is a 914 amino acid protein with α-glucosidase activity that belongs to the glycosyl hydrolase 31 family and hydrolyzes non-reducing, terminal 1,4-linked α-D-glucose residues and releases α-D-glucose. The gene encoding GANC maps to human chromosome 15q15.1, a region associated with susceptibility to non-insulin-dependent (type 2) diabetes mellitus, a disease characterized by high blood glucose levels. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. Function: Has alpha-glucosidase activity. Similarity: Belongs to the glycosyl hydrolase 31 family. Database links: Entrez Gene: 2595 Human Omim: 104180 Human SwissProt: Q8TET4 Human Unigene: 143261 Human Unigene: 730806 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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