產(chǎn)品編號(hào) | bs-13187R-APC |
英文名稱 | Rabbit Anti-FMO5/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的二甲基苯胺單加氧酶5抗體 |
別 名 | Dimethylaniline monooxygenase [N oxide forming] 5; Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; FMO 5; FMO5; FMO5_HUMAN; Hepatic flavin containing monooxygenase 5; Hepatic flavin-containing monooxygenase 5. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 新陳代謝 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, Rat, (predicted: Dog, Pig, Cow, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 60kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FMO5 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Localizing to microsomal and endoplasmic reticulum membranes, FMO5 (flavin containing monooxygenase 5), also known as dimethylaniline monooxygenase [N-oxide-forming] 5, hepatic flavin-containing monooxygenase 5 or dimethylaniline oxidase 5, is a 533 amino acid protein belonging to the FMO family. Expressed in adult and fetal liver, FMO5 is unlike other FMO family members because it does not function as a drug-metabolizing enzyme. FMO5 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1q21.1. Function: In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme. Subcellular Location: Microsome membrane. Endoplasmic reticulum membrane. Tissue Specificity: Expressed in fetal and adult liver. Similarity: Belongs to the FMO family. Database links: Entrez Gene: 2330 Human Entrez Gene: 14263 Mouse Omim: 603957 Human SwissProt: P49326 Human SwissProt: P97872 Mouse Unigene: 642706 Human Unigene: 385180 Mouse Unigene: 7038 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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