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Rabbit Anti-CRISP2/Gold Conjugated antibody (bs-14059R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-14059R-Gold
英文名稱 Rabbit Anti-CRISP2/Gold Conjugated antibody
中文名稱 膠體金標記的富含半胱氨酸分泌蛋白2抗體
別    名 Cancer/testis antigen 36; CRIS2_HUMAN; CRISP 2; CRISP-2; CRISP2; CT36; Cysteine rich secretory protein 2; Cysteine-rich secretory protein 2; GAPDL5; Glyceraldehyde 3 phosphate dehydrogenase like 5; Testis specific protein 1 (probe H4 1 p3 1); Testis specific protein TPX1; Testis-specific protein TPX-1; TPX1; TSP1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  發(fā)育生物學  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CRISP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-2, also known as testis-specific protein TPX1 or cancer/testis antigen 36 (CT36), is a 243 amino acid secreted protein. Expressed in the testis and epididymis, CRISP-2 is thought to be involved in calcium fluxes during sperm capacitation by regulating the activity of certain ion channels. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva. The gene that encodes CRISP-3 is an early response gene that may participate in the pathophysiology of the auto-immune lesions of Sjogren’s syndrome.

Function:
May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.

Subcellular Location:
Secreted.

Tissue Specificity:
Testis and epididymis.

Similarity:
Belongs to the CRISP family.

Database links:

Entrez Gene: 7180 Human

Omim: 187430 Human

SwissProt: P16562 Human

Unigene: 2042 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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