| 產(chǎn)品編號(hào) | bs-12096R-BF488 |
| 英文名稱 | Rabbit Anti-PEX5L/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的過(guò)氧化物酶體生成蛋白5相關(guān)蛋白抗體 |
| 別 名 | Peroxin 5R; PEX5-related protein; Peroxin 5 related protein; Peroxisome biogenesis factor 5 like; PEX2 related protein; PEX5-like protein; PEX5R; Pex5Rp; PEX5R_HUMAN; PEX2-related protein; Peroxin-5-related protein; Pex5Rp; Peroxisome biogenesis factor 5-like; PXR2; PEX5R; PXR2B; PEX5RP; TRIP8b. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 70kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Peroxin 5R |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 5R, also known as PEX5-related protein or Peroxisome biogenesis factor 5-like, is a 626 amino acid protein that is mainly expressed in brain, with some expression in testis and pancreas. Peroxin 5R contains five TPR repeats, which enable protein-protein interactions and assembly of large multiprotein complexes. There are three isoforms of Peroxin 5R that are produced as a result of alternative splicing events. These isoforms bind C-terminal peroxisome-targeting signals in a similar manner to Peroxin-5. Peroxin 5R interacts with Rab 8b, possibly playing a role in vesicular trafficking and neurotransmitter release. Function: Belongs to the peroxisomal targeting signal receptor family. Contains 5 TPR repeats. Subunit: Interacts with RAB8B (By similarity). May interact with the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type); the relevance of such interaction is however unclear. Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity: Mainly expressed in brain. Also expressed in pancreas, testis and pituitary. Similarity: Belongs to the peroxisomal targeting signal receptor family. Contains 5 TPR repeats. Database links: Entrez Gene: 51555 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
