產(chǎn)品編號 | bs-12039R-APC |
英文名稱 | Rabbit Anti-MIR16/APC Conjugated antibody |
中文名稱 | APC標記的膜蛋白相互作用蛋白RGS16抗體 |
別 名 | EC 3.1.4.44; GDE1; Glycerophosphodiester phosphodiesterase 1; Membrane interacting protein of RGS16; RGS16 interacting membrane protein; GDE1_HUMAN. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領域 | 細胞生物 神經(jīng)生物學 信號轉導 細胞膜受體 G蛋白偶聯(lián)受體 G蛋白信號 細胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
產(chǎn)品應用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 38kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MIR16/GDE1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: MIR6 has glycerophosphoinositol phosphodiesterase activity. Subunit: Interacts with RGS16 (By similarity). Interacts with PRAF2. Subcellular Location: Cytoplasmic. Membrane; Multi-pass membrane protein (By similarity). Tissue Specificity: Widely expressed. Post-translational modifications: N-glycosylated Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family. Contains 1 GDPD domain. Database links: Entrez Gene: 51573 Human Omim: 605943 Human SwissProt: Q9NZC3 Human Unigene: 512607 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
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