產(chǎn)品編號 | bs-12056R-PE |
英文名稱 | Rabbit Anti-5HT7 Receptor/PE Conjugated antibody |
中文名稱 | PE標(biāo)記的5-羥色胺受體7抗體 |
別 名 | SR-7; HT 7; 5 HT X; 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled); 5 hydroxytryptamine (serotonin) receptor 7; 5 hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine receptor 7; 5HT7; 5HT7R_HUMAN; HTR7; Serotonin 5 HT 7 receptor; Serotonin receptor 7. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞膜受體 G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 54kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008] Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 3363 Human Entrez Gene: 15566 Mouse Entrez Gene: 100135549 Guinea pig Omim: 182137 Human SwissProt: P50407 Guinea pig SwissProt: P34969 Human SwissProt: P32304 Mouse Unigene: 73739 Human Unigene: 254266 Mouse Unigene: 87132 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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