| 產(chǎn)品編號 | bs-0887R-BF647 |
| 英文名稱 | Rabbit Anti-MV hemagglutinin glycoprotein/BF647 Conjugated antibody |
| 中文名稱 | BF647標(biāo)記的麻疹病毒血凝素抗體 |
| 別 名 | H protein; HA; H; Measles virus hemagglutinin; Hemagglutinin glycoprotein; HEMA_MEASE; MV HA. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 細菌及病毒 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 68kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Measles virus hemagglutinin protein |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
Function: Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell. The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis. Subunit: Interacts with human PVRL4; this interaction allows virus infection of the respiratory epithelium (By similarity). Interacts with human MCP/CD46 antigen and SLAMF1. Subcellular Location: Virion membrane; Single-pass type II membrane protein (Potential). Host cell membrane; Single-pass type II membrane protein (By similarity). Similarity: Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily. Database links: UniProtKB/Swiss-Prot: P08362.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 麻疹病毒血凝素蛋白(Hemagglutinin protein,H)是介導(dǎo)麻疹病毒吸附、侵入宿主細胞的關(guān)鍵分子,麻疹病毒H蛋白在細胞膜上的表達，以及被麻疹病毒感染的細胞和未感染細胞的直接接觸能夠引起其受體CD46的表達下調(diào). |
