| 產(chǎn)品編號(hào) | D50533 |
| 英文名稱 | Triciribine |
| 中文名稱 | 曲西立濱 |
| 別 名 | Triciribine phosphate; VQD-002 (TCN-P); triciribine phosphate; 1-(5-O-Phosphono-β-D-ribofuranosyl)-5-methyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylene-3-amine; 1,5-Dihydro-5-methyl-1-(5-O-phosphono-β-D-ribofuranosyl); 曲西立濱磷酸酯; |
| CAS | 61966-08-3 |
| 理論分子量 | kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Store at -20℃ for one year（Powder）; In DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
CAS號(hào)：61966-08-3 分子式：C13H17N6O7P 分子量：400.286 純度：99.% 溶解性：溶于DMSO。 作用靶點(diǎn)：DNA/RNA Synthesis; Akt; HIV; 作用通路：Cell Cycle/DNA Damage; PI3K/Akt/mTOR; Anti-infection; 描述：曲西立濱 (Triciribine) 是一種DNA synthesis抑制劑，也抑制PC3細(xì)胞系中的Akt和CEM-SS，H9，H9IIIB，U1細(xì)胞中的HIV-1，IC50分別為130 nM和20 nM；對(duì)PI3K/PDK1沒(méi)有抑制作用；作用于缺乏腺苷激酶的細(xì)胞，活性降低5000倍。Phase 1/2。 |
