產(chǎn)品編號(hào) | IHC0364H |
英文名稱 | Human Notch1 Ready-To-Use IHC Kit |
中文名稱 | 人跨膜受體蛋白Notch-1即用型免疫組化試劑盒 |
別 名 | 9930111A19Rik, AOS5, AOVD1, hN1, lin-12, Mis6, Motch, N1, NOTCH1, Notch 1 extracellular truncation, Notch 1 intracellular domain, hN1, Lin-12, LIN12, MIS6, Motch A, mT14, Neurogenic locus notch homolog protein 1, Neurogenic locus notch protein homolog, NI |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
The notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int-3), which have been implicated in the differentiation of the nervous system and other structures. The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including intracellular region (Ntm). SWISS: P46531 Gene ID: 4851 |
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