產(chǎn)品編號 | IHC0344M |
英文名稱 | Mouse Phospho-CDK1/2 (Thr14) Ready-To-Use IHC Kit |
中文名稱 | 小鼠磷酸化周期素依賴性激酶1/2即用型免疫組化試劑盒 |
別 名 | CDC2, Cdc2a, CDK1, p34, Cdc 2, Cdc2, CDC28A, CDK 1, CDK-1, CDK1_HUMAN, CDKN1, CELL CYCLE CONTROLLER CDC2, Cell division control protein 2, Cell division control protein 2 homolog, Cell division cycle 2 G1 to S and G2 to M, Cell division protein kinase 1, |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
CDK1 or Cell Division Control protein 1 is essential for the completion of START, the controlling event in the cell cycle that is required to initiate mitosis. CDK1 is a catalytic subunit of a protein kinase complex, called the M-Phase Promoting Factor that induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated. SWISS: P06493 Gene ID: 983 |
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