| 產(chǎn)品編號 | bsm-63181R |
| 英文名稱 | 14-3-3 alpha/beta/zeta/delta Recombinant Rabbit mAb |
| 中文名稱 | 14-3-3 α/β/ζ/δ重組兔單抗 |
| 別 名 | 14 3 3 protein beta/alpha; 14 3 3 protein zeta; 14 3 3 zeta; 14-3-3 protein/cytosolic phospholipase A2; GW128; HS1; KCIP 1; YWHAB; YWHAD; YWHAZ. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 5B10 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:5000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 28 kDa |
| 檢測分子量 | 28 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human 14-3-3 alpha/beta |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. SWISS: P31946 Gene ID: 7529 信號傳導(dǎo)（Signaling Intermediates）14-3-3蛋白是一個涉及調(diào)節(jié)細(xì)胞凋亡、促細(xì)胞分裂信號傳導(dǎo)和細(xì)胞周期關(guān)卡的蛋白質(zhì)家族。它被認(rèn)為是通過與絲氨酸殘基磷酸化的蛋白質(zhì)的結(jié)合介導(dǎo)的信號傳導(dǎo)中的關(guān)鍵調(diào)節(jié)物。通過與Bad(相關(guān)死亡因子)的結(jié)合， 14-3-3 蛋白由于將Bad隔離于胞液而防止了細(xì)胞凋亡。 蛋白是14-3-3家族成員。它廣泛分布于哺乳動物、兩棲類、昆蟲、植物和酵母菌的真核生物高度保守性多功能蛋白質(zhì)。 目前已知至少有16個成員。此抗體識別分子量為30-31kDa的14-3-3蛋白 |
