產(chǎn)品編號(hào) | bsm-63132R |
英文名稱 | Mono-Methyl-Histone H4 (K17) Recombinant Rabbit mAb |
中文名稱 | 組蛋白H4(單甲基K17)重組兔單抗 |
別 名 | H4; H4/n; H4F2; H4FN; FO108; HIST2H4; H4K16me1. |
抗體來(lái)源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | 4G1 |
交叉反應(yīng) | Human,Mouse |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 11 kDa |
檢測(cè)分子量 | 11 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human Histone H4 around the methylation site of K17 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. SWISS: P62805 Gene ID: 8370 |
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