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VAV3 Recombinant Rabbit mAb (bsm-60661R)  
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產品編號 bsm-60661R
英文名稱 VAV3 Recombinant Rabbit mAb
中文名稱 鳥嘌呤核苷酸交換因子VAV3重組兔單抗
別    名 Guanine nucleotide exchange factor VAV3; Protein vav 3; Protein vav3; VAV 3; VVAV-3; av 3 guanine nucleotide exchange factor; VAV 3 oncogene; VAV 3 protein; VAV-3; VAV3 oncogene; VAV3 protein; VAV3_HUMAN.  
研究領域 信號轉導  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 R2B5
交叉反應 Human (predicted: Mouse,Rat)
產品應用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98 kDa
檢測分子量
細胞定位 細胞漿 細胞外基質 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAV3 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Subcellular Location:
Nucleus.

Tissue Specificity:
Isoform 1 and isoform 3 are widely expressed; both are expressed at very low levels in skeletal muscle. In keratinocytes, isoform 1 is less abundant than isoform 3. Isoform 3 is detected at very low levels, if any, in adrenal gland, bone marrow, spleen, fetal brain and spinal chord; in these tissues, isoform 1 is readily detectable.

SWISS:
Q9UKW4

Gene ID:
10451

Database links:



Entrez Gene: 10451 Human

Entrez Gene: 57257 Mouse

SwissProt: Q9UKW4 Human

SwissProt: Q9R0C8 Mouse





產品圖片
Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:2000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: Human placenta, 2: Mouse placenta, 3: Rat kidney Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 98 kDa Observed MW: 98 kDa
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