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產品編號	bsm-30307A-Pacific Blue
英文名稱	mouse CD45R/Pacific Blue
中文名稱	Pacific Blue標記小鼠CD45R單克隆抗體
抗體來源	Rat
克隆類型	Monoclonal
克隆號	3B6
交叉反應
產品應用	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
性狀	Liquid
亞型	Rat IgG2a, k
純化方法	Affinity purified by Protein G
緩沖液	0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存條件	Store at 2-8℃. Protect from light. Avoid freezing.
注意事項	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
產品介紹	CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. SWISS: P06800 Gene ID: 19264