| 產(chǎn)品編號(hào) | bsm-60426R |
| 英文名稱 | QSOX1 Recombinant Rabbit mAb |
| 中文名稱 | 巰基氧化酶1抗體 |
| 別 名 | QSOX1_HUMAN; Sulfhydryl oxidase 1; QSCN6; EC:1.8.3.2; hQSOX; Quiescin Q6; UNQ2520/PRO6013; quiescin sulfhydryl oxidase 1; Q6; |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | H12B2 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:1000,Flow-Cyt=1:50-1:100
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 80 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | QSOX1屬于FAD依賴的巰基氧化酶家族，是一種非典型的二硫化物催化劑。QSOX1主要定位于人類胚胎成纖維細(xì)胞中的高爾基體和內(nèi)質(zhì)網(wǎng)（ER），它與蛋白質(zhì)二硫鍵異構(gòu)酶（PDI）協(xié)同作用，以幫助將新生蛋白質(zhì)折疊在細(xì)胞中。QSOX1主要在心臟，胎盤，肺，肝，骨骼肌，胰腺中表達(dá)，在腦和腎臟中表達(dá)非常弱。有研究發(fā)現(xiàn)，腫瘤細(xì)胞中QSOX1表達(dá)的增加，使腫瘤細(xì)胞能夠積極規(guī)避由活性氧介導(dǎo)的細(xì)胞凋亡機(jī)制。 |
| 產(chǎn)品圖片 |
Blocking buffer: 5% NFDM/TBST
Primary ab dilution: 1:1000
Primary ab incubation condition:2 hours at room temperature
Secondary ab: Goat Anti-Rabbit IgG H&L (HRP)
Lysate: 1: MCF-7, 2: MDA-MB-231,3: T47D, 4: 293T
Protein loading quantity: 20 μg
Exposure time: 30 s
Predicted MW: 83 kDa
Observed MW: 67 kDa
Cell line: MDA-MB-231
Fixative: 4% Paraformaldehyde
Permeabilization: 90% Methanol
Primary ab dilution: 1:100
Secondary ab: Goat anti Rabbit IgG
Unlabelled control: The cell without incubation with primary antibody and secondary antibody (Black line).
Isotype control: Rabbit monoclonal IgG (Blue line).
Comment: Line red is the positive signal for bsm-60426R
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