| 產(chǎn)品編號(hào) | D-9003 |
| 英文名稱(chēng) | Sulfo-MBS |
| 中文名稱(chēng) | Sulfo-MBS (進(jìn)口，偶聯(lián)劑) |
| 別 名 | m-maleimidobenzoyl-N-hydroxysulfosuccinimide ester; 偶聯(lián)劑; MBS; MMBS; N-(3-MALEIMIDOBENZOYLOXY)SUCCINAMIDE; N-(M-MALEIMIDOBENZOYLOXY)SUCCINAMIDE; N-(M-MALEIMIDOBENZOYLOXY)SUCCINIMIDE; NSC294786; M-MALEIMIDOBENZOICACIDN-HYDROXYSUCCINIMIDEESTER; M-MALEIMIDOBENZOYLN-HYDROXYSUCCINIMIDEESTER; M-MALEIMIDOBENZOYL-N |
| CAS | 92921-25-0 |
| 理論分子量 | kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Store at -20℃. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
MBS and its water-soluble analog Sulfo-MBS are heterobifunctional crosslinkers that contain N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values > 7.5. For these reasons, conjugation experiments involving these crosslinkers are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneously with the maleimide (sulfhydryl-targeted) reaction. 分子式：C15H9O9N2NaS 分子量：416.29 MDL：MFCD00054983 純度：≥80% 性狀：白色粉末。 溶解性：溶于水。 用途：交聯(lián)劑；生化試劑； 分子結(jié)構(gòu)式：
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