| 產(chǎn)品編號(hào) | bs-23044R |
| 英文名稱 | NUCB2 Rabbit pAb |
| 中文名稱 | 新的飽食分子蛋白抗體 |
| 別 名 | NUCB2_HUMAN; Nucleobindin-2; DNA-binding protein NEFA; Epididymis secretory protein Li 109; Gastric cancer antigen Zg4; Prepronesfatin; Nesfatin-1; NEFA; nucleobindin 2; HEL-S-109; |
| 研究領(lǐng)域 | 心血管 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 生長因子和激素 糖尿病 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse,Rat (predicted: Human,Rabbit,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 50 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Nucleobindin 2: 251-350/420 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains. [provided by RefSeq, Oct 2011]. Function: Calcium-binding protein. May have a role in calcium homeostasis. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. Subcellular Location: Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region. Nesfatin-1: Secreted. Tissue Specificity: Predominantly expressed in spleen, testis and normal stomach. Similarity: Belongs to the nucleobindin family. Contains 2 EF-hand domains. SWISS: P80303 Gene ID: 4925 Database links: Entrez Gene: 4925 Human Entrez Gene: 53322 Mouse Omim: 608020 Human SwissProt: P80303 Human SwissProt: P81117 Mouse Unigene: 654599 Human Unigene: 9901 Mouse Unigene: 41602 Rat |
