| 產(chǎn)品編號(hào) | bs-4490R |
| 英文名稱(chēng) | PLB1 Rabbit pAb |
| 中文名稱(chēng) | 磷脂酶B1膜相關(guān)蛋白抗體 |
| 別 名 | hPLB; Lysophospholipase; phospholipase A2; phospholipase B; phospholipase B/lipase; phospholipase B1; phospholipase B1 membrane associated; PLB 1; PLB; PLB/LIP. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 163 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PLB1: 1001-1100/1458 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PLB1 is a membrane-associated phospholipase which exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. It shows preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. It also exhibits esterase activity toward p-nitrophenyl. It may act on the brush border membrane to facilitate the absorption of digested lipids. Function: Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). Subcellular Location: Apical cell membrane; Single-pass type I membrane protein. Note: Present in the intestinal brush border membranes. Tissue Specificity: Expressed in the epidermis (at protein level). Post-translational modifications: Undergoes proteolytic cleavage in the ileum. Similarity: Belongs to the 'GDSL' lipolytic enzyme family. Phospholipase B1 subfamily. SWISS: Q6P1J6 Gene ID: 151056 Database links: Entrez Gene: 151056 Human Omim: 610179 Human SwissProt: Q6P1J6 Human |
