| 產(chǎn)品編號(hào) | bs-19282R |
| 英文名稱 | NLRC3 Rabbit pAb |
| 中文名稱 | 凋亡加強(qiáng)結(jié)構(gòu)域蛋白15樣蛋白抗體 |
| 別 名 | CARD15-like; CARD15-like protein; Caterpiller 16.2; Caterpiller protein 16.2; CLR16.2; FLJ00348; NLR family, CARD domain containing 3; Nlrc3; NLRC3_HUMAN; NOD-like receptor C3; NOD3; NOD3 protein; Nucleotide-binding oligomerization domain protein 3; Nucle |
| 研究領(lǐng)域 | 細(xì)胞生物 結(jié)合蛋白 淋巴細(xì)胞 t-淋巴細(xì)胞 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Pig,Sheep,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 115 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NLRC3: 721-820/1065 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] Function: May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in peripheral blood mononuclear cells. Similarity: Belongs to the NLRP family. Contains 16 LRR (leucine-rich) repeats. Contains 1 NACHT domain. SWISS: Q7RTR2 Gene ID: 197358 Database links: Entrez Gene: 197358 Human Entrez Gene: 268857 Mouse SwissProt: Q7RTR2 Human SwissProt: Q5DU56 Mouse Unigene: 2061102 Human Unigene: 728268 Human Unigene: 215994 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human RAMOS cell lysates
Lane 2: Human MCF-7 cell lysates
Lane 3: Human SH-SY5Y cell lysates
Lane 4: Human Jurkat cell lysates
Primary: Anti-NLRC3 (bs-19282R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 115 kDa
Observed band size: 120 kDa
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