產(chǎn)品編號 | bs-17635R |
英文名稱 | SPATA9 Rabbit pAb |
中文名稱 | 精子發(fā)生相關(guān)蛋白9抗體 |
別 名 | FLJ35906; NYD SP16; spermatogenesis associated 9; Spermatogenesis associated protein 9; Testis development protein NYD SP16. |
研究領(lǐng)域 | 細胞生物 免疫學(xué) 發(fā)育生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse,Rat (predicted: Human,Pig,Sheep,Cow) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 29 kDa |
檢測分子量 | |
細胞定位 | 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SPATA9: 121-200/254 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
SPATA9 is a 254 amino acid single-pass membrane protein that is highly expressed in testis and pancreas with low expression in heart, lung, and brain. A component of the sperm acrosome, SPATA9 may participate in sperm capacitation and acrosome reaction, and is therefore necessary for fertilization. SPATA9 is also suggested to be involved in testicular development/spermatogenesis and may be an important factor in male infertility. No expression of SPATA9 was found in patients affected by Sertoli-cell-only syndrome, also known as Del Castillo syndrome or germ cell aplasia, which is characterized by male sterility without sexual abnormality. SPATA9 is encoded by a gene located on human chromosome 5, which consists of about 181 million base pairs, encodes around 1,000 genes and represents about 6% of human genomic DNA. Function: SPATA9 may play a role in testicular development/spermatogenesis and may be an important factor in male infertility. Three named isoforms exist. Subcellular Location: Membrane; Single-pass membrane protein SWISS: Q9BWV2 Gene ID: 83890 Database links: Entrez Gene: 83890 Human Omim: 608039 Human SwissProt: Q9BWV2 Human |
產(chǎn)品圖片 |
Sample: Testis (Mouse) Lysate at 40 ug
Primary: Anti-SPATA9 (bs-17635R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 19 kD
Sample: Cerebrum (Rat) Lysate at 40 ug
Primary: Anti-SPATA9 (bs-17635R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 19 kD
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