| 產(chǎn)品編號(hào) | bs-16408R |
| 英文名稱 | ZRSR2 Rabbit pAb |
| 中文名稱 | ZRSR2蛋白抗體 |
| 別 名 | CCCH type zinc finger, RNA binding motif and serine/arginine rich protein 2; MGC142014; U2AFM_HUMAN; MGC142040; Renal carcinoma antigen NY REN 20; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2; U2(RNU2) small nuclear RNA auxiliary factor 1 like 2; U2AF1 RS2; U2AF1L2; U2AF1RS2; U2AF35-related protein; URP; Zinc finger-, CCCH domain-, and RNA-binding motif-containing serine/arginine-rich protein 2. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 58 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZRSR2: 351-450/482 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008] Function: ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally redundant. Subunit: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Interacts (via RS domain) with SRSF1 and SRSF2. Interacts with U2AF2/U2AF65. Subcellular Location: Nuclear Tissue Specificity: Widely expressed. Post-translational modifications: Phosphorylated in the RS domain by SRPK1. Similarity: Contains 2 C3H1-type zinc fingers. Contains 1 RRM (RNA recognition motif) domain. SWISS: Q15696 Gene ID: 8233 Database links: Entrez Gene: 8233 Human Entrez Gene: 22184 Mouse Omim: 300028 Human SwissProt: Q15696 Human SwissProt: Q62377 Mouse Unigene: 171909 Human Unigene: 426178 Mouse Unigene: 26786 Rat |
