| 產(chǎn)品編號(hào) | bs-16352R |
| 英文名稱 | GTF2H3 Rabbit pAb |
| 中文名稱 | 通用轉(zhuǎn)錄因子2H亞基3/TTFIIH p34抗體 |
| 別 名 | Basic transcription factor 2 34 kDa subunit; BTF2; BTF2 p34; General transcription factor IIH polypeptide 3; General transcription factor IIH subunit 3; general transcription factor IIH, polypeptide 3, 34kDa; Gtf2h3; P34; TF2H3_HUMAN; TFB4; TFIIH; TFIIH basal transcription factor complex p34 subunit; Transcription factor IIH 34 kDa subunit. |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse,Chinese Hamster) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 34 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GTF2H3: 1-100/308 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012] Function: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB. Subcellular Location: Nucleus. Similarity: Belongs to the TFB4 family. SWISS: Q13889 Gene ID: 2967 Database links: Entrez Gene: 2967 Human Entrez Gene: 100059174 Horse Entrez Gene: 209357 Mouse Omim: 601750 Human SwissProt: Q13889 Human SwissProt: Q8VD76 Mouse Unigene: 355348 Human Unigene: 185467 Mouse Unigene: 203542 Rat |
