| 產(chǎn)品編號 | bs-14348R |
| 英文名稱 | DMRTA2 Rabbit pAb |
| 中文名稱 | DMRTA2蛋白抗體 |
| 別 名 | DMRT A2; DMRT like family A2; DMRT5; DMRTA 2; dmrta2; DMTA2_HUMAN; Doublesex-and mab-3-related transcription factor 5; Doublesex-and mab-3-related transcription factor A2. |
| 研究領(lǐng)域 | 細(xì)胞生物 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 53 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DMRTA2: 21-120/542 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: May be involved in sexual development. Subcellular Location: Nucleus. Tissue Specificity: Expressed in testis. Similarity: Belongs to the DMRT family. Contains 1 DM DNA-binding domain. SWISS: Q96SC8 Gene ID: 63950 Database links: Entrez Gene: 63950 Human Entrez Gene: 242620 Mouse SwissProt: Q5TFQ3 Human SwissProt: Q96SC8 Human SwissProt: A2A9A2 Mouse Unigene: 334481 Human Unigene: 32825 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Human Jurkat cell lysates
Lane 2: Human SH-SY5Y cell lysates
Lane 3: Human U-2 OS cell lysates
Primary: Anti-DMRTA2 (bs-14348R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kDa
Observed band size: 54 kDa
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