| 產(chǎn)品編號 | bs-13583R |
| 英文名稱 | ZBTB7C Rabbit pAb |
| 中文名稱 | 鋅指蛋白ZBTB7C抗體 |
| 別 名 | APM 1; APM1; B230208J24Rik; FLJ37907; ZBTB36; Zinc finger and BTB domain containing 7C. |
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Specific References (1) | bs-13583R has been referenced in 1 publications.
[IF=3.375] Xuenuo Chen. et al. Zinc finger and BTB domain-containing 7C (ZBTB7C) expression as an independent prognostic factor for colorectal cancer and its relevant molecular mechanisms. Am J Transl Res. 2020; 12(8): 4141–4159 IHC ; Human.
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| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Chicken,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 69 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZBTB7C: 351-450/619 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Zinc finger and BTB domain-containing protein 7C (ZBTB7C), also designated affected by papillomavirus DNA integration in ME180 cells protein 1 (APM-1), contains 1 BTB (POZ) domain and 4 C2H2-type zinc fingers. ZBTB7C is detected in normal cervical keratinocytes and may be a potential tumor suppressor gene against human papillomavirus (HPV) mediated cervical carcinogenesis. Function: The function of Anti-ZBTB7C has not yet been determined. Tissue Specificity: Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines. Similarity: Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers. SWISS: A1YPR0 Gene ID: 201501 Database links: Entrez Gene: 201501 Human Entrez Gene: 207259 Mouse SwissProt: A1YPR0 Human SwissProt: Q8VCZ7 Mouse Unigene: 515388 Human |
| 產(chǎn)品圖片 |
Sample: A549 (human)Cell Lysate at 40 ug
Primary: Anti-ZBTB7C(bs-13583R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 69 kD
Observed band size: 63 kD
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