產(chǎn)品編號(hào) | bs-11362R |
英文名稱(chēng) | SNAP23 Rabbit pAb |
中文名稱(chēng) | 突觸相關(guān)蛋白23抗體 |
別 名 | SNAP 23; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23_HUMAN; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Synaptosomal associated protein; Synaptosomal-associated protein 23; Vesicle membrane fusion protein SNAP 23; Vesicle membr |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 細(xì)胞膜蛋白 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 23 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SNAP23: 101-200/211 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Function: Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion. Subunit: Homotetramer (via coiled-coil domain), also forms heterotetramers with STX4 and VAMP3. Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A. Subcellular Location: Cell membrane. Cell membrane. Cell junction > synapse > synaptosome. Mainly localized to the plasma membrane. Tissue Specificity: Ubiquitous. Highest levels where found in placenta. Similarity: Belongs to the SNAP-25 family. Contains 2 t-SNARE coiled-coil homology domains. SWISS: O00161 Gene ID: 8773 Database links: Entrez Gene: 453365 Chimpanzee Entrez Gene: 101141000 Gorilla Entrez Gene: 8773 Human Entrez Gene: 20619 Mouse Entrez Gene: 100174679 Orangutan Omim: 602534 Human SwissProt: O00161 Human SwissProt: O09044 Mouse Unigene: 511149 Human Unigene: 245715 Mouse Unigene: 14789 Rat |
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