| 產(chǎn)品編號 | bs-6607R |
| 英文名稱 | TSPY1 Rabbit pAb |
| 中文名稱 | 睪丸特異定蛋白質(zhì)編碼Y1抗體 |
| 別 名 | DYS14; pJA 923; pJA923; Testis specific protein Y linked 1; Testis specific Y encoded protein 1; TSPY 1; TSPY; TSPY1_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 發(fā)育生物學(xué) 染色質(zhì)和核信號 干細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 34 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TSPY1: 231-308/308 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The function of this protein is unknown. TSPY genes are located on the Y-chromosome of several mammalian species. TSPY encodes a testis-specific protein 1, which probably acts as nucleosome-binding transcription factor. Homology with the SET/NAP/DENTT oncogene family suggest a role in spermatogonic cell division and seminal oncogenesis. Function: May be involved in sperm differentiation and proliferation. Subcellular Location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Also found in nucleus. Tissue Specificity: Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines. Post-translational modifications: Phosphorylated. Similarity: Belongs to the nucleosome assembly protein (NAP) family. SWISS: Q01534 Gene ID: 728137 Database links: Entrez Gene: 7258 Human Entrez Gene: 728137 Human Omim: 480100 Human SwissProt: Q01534 Human Unigene: 556121 Human |
