產(chǎn)品編號(hào) | bs-0362P-PE |
英文名稱 | Recombinant protein A |
中文名稱 | PE標(biāo)記蛋白A |
別 名 | Protein A / PE |
理論分子量 | kDa |
檢測分子量 | |
性 狀 | Liquid |
物 種 | S.aureus |
序 列 | Purified native protein |
內(nèi)毒素 | Not analyzed |
活性 | Yes |
緩 沖 液 | 10 mM TBS (pH=7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Stored at 2-8℃ for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Protein A is a surface protein of S.aureus which binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology. |
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