產(chǎn)品編號 | bs-0898R |
英文名稱 | intestinal FABP Rabbit pAb |
中文名稱 | 小腸型脂肪酸結(jié)合蛋白抗體 |
別 名 | FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; I FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; OTTHUMP00000163925. |
研究領(lǐng)域 | 免疫學(xué) 生長因子和激素 激酶和磷酸酶 糖尿病 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Chicken) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 28 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human IFABP: 31-132/132 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity). [Subcellular Location] Cytoplasm (By similarity). [Similarity] Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Function: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. SWISS: P12104 Gene ID: 2169 Database links: Entrez Gene: 2169 Human Entrez Gene: 14079 Mouse Omim: 134640 Human SwissProt: P12104 Human SwissProt: P55050 Mouse SwissProt: Q53YP5 Mouse Unigene: 282265 Human Unigene: 28398 Mouse Unigene: 91358 Rat 小腸脂肪酸結(jié)合蛋白(IFABP)主要是在小腸分泌的一種蛋白質(zhì),參與了脂肪酸的吸收和代謝。IFABP有可能通過干擾脂肪酸代謝而影響胰島素敏感性。 IFABP主要用于2型糖尿病相關(guān)性的研究。 |
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