產(chǎn)品編號 |
bs-1554R |
英文名稱 |
Rabbit Anti-Aquaporin 5 antibody
|
中文名稱 |
水通道蛋白5抗體 |
別 名 |
Aquaporin 5; AQP5; AQP 5; AQP-5; AQP5_HUMAN; Aquaporin-5. |
 |
Specific References (10) | bs-1554R has been referenced in 10 publications.
[IF=5.23] Yi, TacGhee, et al. "Single Cell Clones Purified from Human Parotid Glands Display Features of Multipotent Epitheliomesenchymal Stem Cells." Scientific Reports 6 (2016). FCM ; Human.
[IF=4.25] Lim, Jae-Yol, et al. "Establishment and Characterization of Mesenchymal Stem Cell-like Clonal Stem Cells from Mouse Salivary Glands." Tissue Engineering (2014). Mouse.
[IF=3.419] Shota Mitsuboshi. et al. A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy. Regen Ther. 2022 Mar;19:113 IHC ; Rat.
[IF=2.826] Takanori Watanabe et al. Aquaporin 3 Expression in Endometrioid Carcinoma of the Uterine Body Correlated With Early Stage and Lower Grade. Pathol Oncol Res. 2020 Oct;26(4):2247-2253. IHC ; Human.
[IF=2.634] Liu X. et al. Effects of Different Ligands in the Notch Signaling Pathway on the Proliferation and Transdifferentiation of Primary Type II Alveolar Epithelial Cells.. Front Pediatr. 2020 Aug;8:452-452 WB ; Rat.
[IF=2.311] Haifa Alkhalifa. et al. Inhibition of aquaporins as a potential adjunct to breast cancer cryotherapy. Oncol Lett. 2021 Jun;21(6):1-11 WB ; Human.
[IF=2.041] Wang D et al. Suppression of high-mobility group box 1 ameliorates xerostomia in a sjogren syndrome-triggered mouse model. Can J Physiol Pharmacol. 2020 Jan 14. WB ; Mouse.
[IF=1.935] Sato K et al. Different Prognostic Implications of Aquaporin-1 and Aquaporin-5 Expression among Different Histological Types of Ovarian Carcinoma.Pathol Oncol Res. 2018 Jul 19. IHC-P ; Human.
[IF=1.248] Wei W et al. Estradiol Induced Estrogen Receptor-mediated Transcription and Expression of Aquaporin5.Chemical Research in Chinese Universities,2019 35(2), 239–244. WB,ICF&IHC-P ; Mouse&Human.
[IF=1.09] Wang, Wei, et al. "Expression of AQP5 and AQP8 in human colorectal carcinoma and their clinical significance." World journal of surgical oncology 10.1 (2012): 1-5. IHC-P ; Human.
|
研究領(lǐng)域 |
信號轉(zhuǎn)導(dǎo) 通道蛋白 上皮細(xì)胞 |
抗體來源 |
Rabbit |
克隆類型 |
Polyclonal
|
交叉反應(yīng) |
Mouse,Rat
|
產(chǎn)品應(yīng)用 |
WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
理論分子量 |
29 kDa |
檢測分子量 |
|
細(xì)胞定位 |
細(xì)胞膜
|
性 狀 |
Liquid |
濃 度 |
1mg/ml |
免 疫 原 |
KLH conjugated synthetic peptide derived from mouse AQP5: 201-265/265 <Cytoplasmic> |
亞 型 |
IgG |
純化方法 |
affinity purified by Protein A |
緩 沖 液 |
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed |
PubMed |
產(chǎn)品介紹 |
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
Function: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
Subcellular Location: Membrane; Multi-pass membrane protein.
Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family.
SWISS: Q9WTY4
Gene ID: 11830
Database links:
Entrez Gene: 362 Human
Entrez Gene: 11830 Mouse
Entrez Gene: 25241 Rat
Omim: 600442 Human
SwissProt: P55064 Human
SwissProt: Q9WTY4 Mouse
SwissProt: P47864 Rat
Unigene: 298023 Human
Unigene: 45580 Mouse
Unigene: 10066 Rat
水通道蛋白(Aquaporin,AQP)是一組與水分子通透有關(guān)的特異性細(xì)胞膜轉(zhuǎn)運(yùn)蛋白。其中,AQP 5在哺乳動物氣管、支氣管的上皮細(xì)胞表達(dá)較常見.
|
產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Lung tissue lysates
Lane 2: Rat Stomach tissue lysates
Primary: Anti-Aquaporin 5 (bs-1554R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kD
Observed band size: 27 kD
|
|
|