| 產(chǎn)品編號(hào) | bs-1058R |
| 英文名稱(chēng) | LIF Rabbit pAb |
| 中文名稱(chēng) | 白血病抑制因子抗體 |
| 別 名 | Leukemia inhibitory factor; DIA; CDF; Cholinergic Differentiation Factor; D factor; differentiation inhibitory activity; Differentiation stimulating factor; Emfilermin; HILDA; Human interleukin in DA cells; LIF_HUMAN; Melanoma derived LPL inhibitor; Melanoma-derived LPL inhibitor; MLPLI. |
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Specific References (7) | bs-1058R has been referenced in 7 publications.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 生長(zhǎng)因子和激素 細(xì)胞周期蛋白 細(xì)胞分化 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Rabbit,Pig,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LIF: 101-202/202 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The leukemia inhibitory factor- LIF is a kind of cell factor that has various living creature functions.It has the leukemia cell of inducement to divide, regulating the growth metabolism of the bone organization, maintaining the basic characteristic of the Embryonicstem celles and promoting the mankind build the blood stem cell to divide to propagate, promote the cholinergic neuron to divide, obstruct the fat cell to synthesize, stimulate the muscle cell growth, regulate the liver cell to expect to respond the egg white to synthesize etc. in the acute the biology activity etc. function. Function: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes. Subcellular Location: Secreted. Similarity: Belongs to the LIF/OSM family. SWISS: P15018 Gene ID: 3976 Database links: Entrez Gene: 3976 Human Entrez Gene: 16878 Mouse Omim: 159540 Human SwissProt: P15018 Human SwissProt: P09056 Mouse Unigene: 2250 Human Unigene: 4964 Mouse 生長(zhǎng)因子和激素（ Growth Factor and Hormones） 白血病抑制因子-LIF是一種具有多種生物功能的細(xì)胞因子。它具有誘導(dǎo)白血病細(xì)胞分化，調(diào)節(jié)骨組織的生長(zhǎng)代謝，維持胚胎干細(xì)胞（Embryonicstem celles細(xì)胞）的基本特征、促進(jìn)人類(lèi)造血干細(xì)胞的分化增殖、促進(jìn)膽堿能神經(jīng)元的分化、阻礙脂肪細(xì)胞合成、刺激成肌細(xì)胞生長(zhǎng)、調(diào)節(jié)肝細(xì)胞中急性期反應(yīng)蛋白的合成等生物學(xué)活性等作用. |
| 產(chǎn)品圖片 |
Sample:
Large intestine(mouse) Lysate at 40 ug
U87mg cell(human) Lysate at 30 ug
Primary: Anti- LIF (bs-1058R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20kD
Observed band size: 30/50 kD
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